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Sandimmune Injection 100mg/1ml

Generic Cyclosporine

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Starting from $2.88

Sandimmune injection 100mg contains cyclosporine as a main component. It is a cyclic polypeptide immunosuppressant agent containing 11amino acids produced by fungus Beauveria nivea. This injection is available in a 5 ml ampoule and is diluted with 0.9% sodium chloride injection while taking this injection. It is used to prevent organ transplant rejection.

Quantity Strength Price Unit Price
50ml Sandimmune Injection 100mg/1ml - Cyclosporine $143.88 $2.88

Sandimmune Injection 100mg/1ml functions by inhibiting the production and release of interleukin-2, which is important in both cellular and humoral responses. When Interleukin 2 is inhibited, it suppresses humoral immunity, cell-mediated reactions such as allograft rejection, delayed hypersensitivity etc.

Sandimmune injection 100mg is contraindicated in following conditions-

  • This injection is contraindicated in case of a person allergic to cyclosporine.
  • Potassium sparing diuretics should not be consumed while taking this injection.
  • Breast feeding mother should avoid this injection.
  • This injection is contraindicated in case of pregnant women.
  • Person suffering from liver and kidney disease should not consume this injection.
  • Avoid this injection in case of a person suffering from high blood pressure.

Various drugs that should not be consumed with Sandimmune injection 100mg are-

  • HIV protease inhibitor- Ritonavir, Saquinavir
  • Anti tuberculosis drugs- Rifampin, Ethambutol
  • Potassium sparing diuretics- Spironolactone
  • Non steroidal anti-inflammatory drugs- Ibuprofen, Salicylic acid
  • Calcium channel blockers- Nifedipine , Verapamil
  • H2 antihistamine drugs- Cimetidine, Ranitidine
  • Anti epileptic drugs- Carbamazepine, Phenytoin

Storage condition of Sandimmune injection

  • This injection should be stored in refrigerator.
  • It should be stored away from direct sunlight, heat and moisture.

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Initially a dose of 15mg per kg is given 4 to 12 hours before .This initial single daily dose is continued for 1 to 2 weeks and then lessened by 5% per week to a maintenance dose of 5 to 10 mg/kg/day.

In case if overdose of this injection is consumed, then some overdose symptoms may occur such as-

  • Headache
  • Nausea, vomiting
  • Increased hair growth on hands ,face
  • Swelling of gum tissue
  • Muscle pain and cramps

Sandimmune injection 100mg may show various side effects such as-

  • Pain, numbness in the hands and legs
  • Uncontrolled shaking of body parts
  • Shortness of breadth
  • Arrhythmia
  • Difficulty in swallowing

Safety tips that should be followed while taking Sandimmune injection are-

  • Avoid intake of grapefruit and grape juice while taking this injection.
  • A person taking this injection should not take prescription and nonprescription drugs.
  • If a person ever had low level of cholesterol or magnesium in the blood, then this injection should be taken with caution.
  • Cyclosporine may cause Hyperkalemia so this injection should be taken after consulting a doctor.
  • Do not take vaccines without consulting a doctor, if a person is taking this injection.
  • Cyclosporine causes extra gum growth so brushing of the teeth should be done carefully.