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Pyzina 500mg Tablets | Generic Pyrazinamide


Generic Pyrazinamide 500mg

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Starting from $0.32

Pyzina is an antibiotic that is prescribed for the treatment of tuberculosis (a serious lung inflammation that mainly affects the lungs).This medicine is taken with other medicines to give relief in condition by preventing the spread of bacteria in the body.The main key compound present in Pyzina is Pyrazinamide that is FDA approved. Pyzina is usually taken in combination with other anti-tuberculosis drugs like Rifampicin, Isoniazid, and either Streptomycin or Ethambutol for the management of active tuberculosis.

Quantity Strength Price Unit Price
30 Tablet/s Pyzina 500mg - Generic Pyrazinamide $11.15 $0.37
60 Tablet/s Pyzina 500mg - Generic Pyrazinamide $20.05 $0.33
90 Tablet/s Pyzina 500mg - Generic Pyrazinamide $28.70 $0.32

FUNCTIONING OF PYZINA 500 MG IN THE BODY–

Pyrazinamide is a nicotinamide analog that acts by blocking the development of Mycobacterium tuberculosis­- a bacteria responsible for tuberculosis disease. It goes inside the granuloma of m. tuberculosis and then tuberculosis enzyme Pyrazinamidase is changed into Pyrazinamide. Lastly, it gets converted into Pyrazinoic acid. Pyrazinoicacid inhibits the functioning of fatty acid synthase (FAS) I enzyme that is essential for the bacteria produce fatty acids. This causes the disruption of membrane potential and blocks the energy creation, which is necessary for the survival of M. tuberculosis.

DOSING RECOMMENDATION OF PYZINA 500 MG–

Pyzina is best available in dosing strength of 500 mg in a tablet formulation. For the management of tuberculosis, it is advised to ingest Pyzina 1000 to 2000 mg, once on daily basis. This medicine is working effectively when combined with three other three antibiotics for first 2 months of a 6 month or 9-month treatment until the tests of drug susceptibility prove known. Take it orally with an abundance of water. To know more about the dosing consult with the doctor.

SIDE EFFECTS THAT CAN COME IN VIEW WITH THE USE OF PYZINA 500 MG–

Common noticed negative effects of Pyzina 500 mg are a loss of appetite, unusual tiredness or weakness, skin or color of eyes turns yellow, pain in large or small joints, skin rash, and itching. These side effects may persist along with the treatment, but do not cause any serious complications to the patients.

CONTRAINDICATIONS OF PYZINA 500 MG–
  • Pregnant or nursing mothers are not allowed to take Pyzina as it may affect the baby.
  • Pyzina is completely contraindicated in case of having an allergy to any of its components as t may cause unwanted side effects.
  • The use of Pyzinastrictly prohibited in patients who are going through active gout or severe liver diseases.
CAUTIONARY STEPS TO BE FOLLOWED WHILE USING PYZINA 500 MG
  • Taking Pyzina with other anti-T.B. medicines, it is advised to monitor liver functioning and serum uric acid before and during therapy.
  • It is advised not to take alcohol while being on Pyzina as it may cause unwanted side effects.
  • It is crucial for diabetic patients to closely monitor their blood sugar level while relying on the treatment of Pyzina medicine.
  • People with HIV or AIDS or diabetes should seek advice from a doctor before using this medicine. 

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