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Tofranil (25mg, 75mg) | Generic Imipramine

Imipramine - Tofranil

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Tofranil 25mg is an excellent tricyclic antidepressant medication used in the treatment of depression. It helps to improve mood, sleep, appetite, and energy level and may help re-establish the interest in everyday living. Tofranil medication is also used as an adjunctive therapy in reducing enuresis (bedwetting) in children aged 6 years and older. Tofranil 25mg encloses a generic drug called Imipramine. 

Quantity Strength Price Unit Price
90 Tablets Tofranil 25mg $8.99 $0.10
120 Tablets Tofranil 25mg $12.99 $0.11
30 Tablets Tofranil 75mg $9.99 $0.33
90 Tablets Tofranil 75mg $26.99 $0.30

How does Tofranil 25mg work?

Imipramine belongs to the category of medication called tricyclic antidepressants. It exhibits its curative effect by blocking the neuronal reuptake of the neurotransmitters norepinephrine and serotonin. Thus, reducing the reuptake of these neurotransmitters enhances their concentration in the synaptic cleft, which helps to relieve the symptoms of depression.

What is the dosing plan of Tofranil 25mg?

Tofranil 25mg is commercially accessible in a tablet formulation. Dose for hospitalized patients: In the beginning, a dose of 100mg of Tofranil per day is given to hospitalized patients with depression and the dose is gradually enhanced to 200 mg/day as required. If no response after two weeks occurs, then enhance the dose to 250 to 300 mg/day. Dose for outpatients with depression: Initially, a patient has to take 75mg of Tofranil in a day and the dose may be enhanced to 150mg/ day, but the dosages over 200 mg/day are not recommended. 

Dose for the management of Childhood enuresis: A dose of 25 mg/day should be given via the oral route one hour before bedtime to children aged six and older. If a reasonable response does not occur within one week, enhance the dose to 50 mg nightly in children less than 12 years and the children over 12 may be given up to 75 mg nightly.

Who should not take Tofranil 25mg?

  • Do not use Tofranil 25mg if you are hypersensitive to generic Imipramine or any other components of Tofranil 25mg.
  • Do not use you Tofranil 25mg if you have taken Linezolid or a monoamine oxidase inhibitor within the last 14 days.
  • Do not use Tofranil 25mg if you are you are recovering from a current heart attack.

What are the undesired effects of Tofranil 25mg?

A patient may suffer from some undesired effects while relying on the treatment of Tofranil 25mg such as lightheadedness, sleepiness, dry mouth, headache, impotence, nausea, pupil dilation, sweating, tiredness, upset stomach, vomiting, weakness, alteration in body weight.

What are the possible drug interactions of Tofranil 25mg?

Some medicines that show drug interaction generic Imipramine such as Phenelzine, Phenobarbital, Phenytoin, Benztropine, Cimetidine, Fentanyl, Flecainide, Lithium, St. John's Wort, Tramadol, Fluoxetine, Duloxetine, Clonidine, and Guanethidine.

What are the safety measures to be followed while using Tofranil 25mg?

  • The use of Tofranil medication may cause drowsiness or dizziness, so do not drive a vehicle or carry out any risky tasks after using this medicine.
  • Avoid the intake of alcohol or sleeping pills while relying on the treatment of Tofranil medication.
  • Do not recommend this medication to children under 6 years old to treat their childhood enuresis.
  • If you are a pregnant woman or a lactating mother, then consult a doctor before using this medicine. 

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