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Tadalafil with Dapoxetine Tablets


Tadalafil With Dapoxetine Tablets

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Starting from $0.75

Tadalafil with Dapoxetine Tablets are combinational therapy used in the treatment of erectile dysfunction and premature ejaculation

Quantity Strength Price Unit Price
30 Tablets TADALAFIL-DAPOXETINE TABLETS $25.00 $0.83
60 Tablets TADALAFIL-DAPOXETINE TABLETS $45.00 $0.75
120 Tablets TADALAFIL-DAPOXETINE TABLETS $98.00 $0.82

Erectile dysfunction (ED) and Premature ejaculation (PE) is one of the common disorders developed in the male. Many factors are responsible for these disorders like:

  • stress
  • diabetes
  • obesity
  • work load
  • severe injury
  • use of alcohol and tobacco

Tadalafil with Dapoxetine are the therapy, which is used to treat ED and PE in male (adult). Tadalafil is known to be an active ingredient and come under the classification of Phosphodiesterase 5 inhibitor which is useful to treat ED. Whereas, Dapoxetine is also an active ingredient which comes under the classification of serotonin reuptake inhibitor which is useful to treat PE.

Mechanism of action:

Both the component, i.e. Tadalafil with Dapoxetine comes under the separate classes. So, they possess different mode of action.

Tadalafil: During the sexual intercourse, nitric acid is released and simultaneously the guanylate cyclase is converted into the cyclic Guanosine monophosphate(cGMP), which is responsible the relaxation of the blood vessels into the targeted part of the body. At the same time, PDE 5 stimulated and inhibits the action of cGMP. At that time, Tadalafil became active to inhibit the action of PDE5 and stimulates the action of the cGMP. Due to which, the relaxation of the blood vessels takes place, which increases the blood circulation into the targeted part of the body?


Dapoxetine: It acts by inhibiting the reuptake of serotonin which is responsible for the produces a reflex action to stimulate the ejaculation. Dapoxetine inhibits the serotonin reuptake; because of this action it increases the serotonin level in the nervous system. Thus, as the level of serotonin increases, the activity of the serotonin enhances simultaneously in the nervous system. Then finally it helps to enhance the time of ejaculation.

Contraindications:

In Some conditions the drug should be contraindicated such as

  • Having cardiovascular diseases.
  • Along with drugs like Nitrates or Thiozolidine.
  • Patient suffering from kidney disorder or hepatic disorder.
  • If the patient already has its typical ejaculation or erection naturally.
  • Hypersensitivity problems with the active ingredients present in the medication.

Drug interactions:

The person should avoid the consumption of certain class of drug while taking this such as

  • Nitrates like Isosorbide mononitrate
  • Anti fungal drugs like Fluconazole
  • Thiozolidine
  • Mono amine oxidase inhibitors
  • herbal products with serotonergic effects
  • CNS active medicinal product

Storage:

  • Tadalafil with Dapoxetine should be stored at clean and the storage temperature varied from 15- 30° C.
  • It should be kept in dark and dry condition.
  • Should be kept away from the children.
  • Discard the expired product.

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Dose and mode of administration:

The Recommended dose to get its best therapeutic effect is once in a day before half an hour while having the sexual intercourse. The dose should be adjusted for those patients having any medical history or for elderly patients.


Tadalafil with Dapoxetine is a solid dosage form, so it is taken by an oral route with a full glass of water with or without food. Tadalafil with Dapoxetine has rapid onset of action, i.e. within a half hour, and remains its effect for 36 hrs.

Overdose:

The patient should not take it more than the recommended dose in any condition. Tadalafil with Dapoxetine should be administered one tablet within 24 hrs.


The sign and symptoms occur after an overdose:

  • Heaviness in head or migraine
  • Dyspepsia
  • Sensation of pain ( back, muscles, chest)
  • Nasal congestion
  • Arrhythmias

Missed dose:

There is no or less chance for missing any dose, as it administered only when it is necessary.


The sign and symptoms occur after overdose:

  • Heaviness in head or migraine
  • Dyspepsia
  • Sensation of pain ( back, muscles, chest)
  • Nasal congestion
  • Arrhythmias

In such condition person should avoid the consumption of extra dose than the recommended. In such symptoms person should take medical help.

Common Side effects:

  • Cough
  • Migraine
  • Hypersensitivity problem
  • Tenderness
  • Painful erection
  • Swelling or inflammation on face

Precautions While taking this drug

  • The patient should not take more than the recommended dose in any condition. Tadalafil with Dapoxetine should be administered one tablet within 24 hrs.
  • The person should maintain a gap of at least 24 hours.
  • This drug makes the person sleepy as don't indulge in the work that requires alertness.