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Aleve is a nonsteroidal anti-inflammatory drug. The active medication of the drug is Naproxen 250mg which works by reducing hormones which cause inflammation and pain in the body. Naproxen is used in the treatment of pain or inflammation caused by arthritis, ankylosing spondylitis, bursitis, tendinitis, menstrual cramps, gout.

Quantity Strength Price Unit Price
30 Tablets Aleve 250mg $10.99 $0.37
90 Tablets Aleve 250mg $20.99 $0.23
30 Tablets Aleve 500mg $11.99 $0.40
90 Tablets Aleve 500mg $21.99 $0.24

The active medication of Aleve that is Naproxen 250mg works by inhibiting the synthesis of prostaglandins in the body tissues by inhibiting the activity of cyclooxygenase (COX) iso-enzymes, COX-1 and COX-2. The antiinflammatory activity of the naproxen is shown by the inhibition of chemo taxis and by altering lymphocyte activity. Naproxen decreases proinflammatory cytokine activity, and inhibit neutrophil aggregation; these effects also imparts anti-inflammatory activity.

How to use Aleve?

The extended release form or enteric coated tablet of the mediaction should not be crushed, chewed, or break. The pill should be swallowed as a whole. The extended-release pill is specially designed for the slow release of medicine in the body. If the oral suspension of the medication is under use, the bottle of the liquid should be shaken well before use.

When not to use naproxen 250mg

There are some conditions in which naproxen 250 mg is contraindicated. Some of them are mentioned as follows:

  • If the patient is allergic to aspirin, use of Naproxen 250mg is contraindicated.
  • If the patient has undergone coronary artery bypass graft (CABG) surgery and suffering from perioperative pain.
  • If the person is having bleeding disorders, hepatic disease, peptic ulcer, stomatitis like disease conditions, use of naproxen is contraindicated.
  • In case of late pregnancy means premature closure of ductus arteriosus occur, use of naproxen is strictly contraindicated.

Drugs that show interactions with Naproxen 250mg

Naproxen 250mg shows interaction with the following kind of medications:

Antidepressant drugs like citalopram, citalopram, fluoxetine, fluvoxamine, paroxetine, sertraline, trazodone, vilazodone, blood thinners like warfarin, methotrexate, diuretics like furosemide, steroids like prednisone.

Storage conditions of Naproxen 250mg

This medication should be stored properly at room temperature and away from moisture and heat.

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How to manage missed dose of Naproxen 250mg?

If patient is taking medication regularly, and a dose is missed, it should be taken as soon as remember. But if the time of next dose has been reached, missed dose should be skipped and next dose should be taken at the regular time. Extra medication should not be taken to make up the missed dose.

How to manage the condition when overdosing of the medication occurs?

  • Overdosing should never be done. In case if overdosing symptom appears, visit to the hospital immediately.

Undesired effects shown by the naproxen 250mg

Common Side effects includes: spots, trouble in breathing, swelling of lips and tongue, throat swelling. If this allergic reaction persists, medical help can be taken.

Severe side effect includes:

Pain in chest, weakness, shortness of breath, slurred speech, vision problems, Bloody stools, swelling or gain in weight, less or dark urination, nausea, pain in stomach, loss of appetite, dark urination, itching, jaundice, numbness, muscle weakness, headache, fever, chills, increased sensitivity towards light, convulsions, sore throat, burning of eyes.

The key points which are to be taken as precautionary measures of Naproxen 250mg:

  • Do not take alcohol in excessive amount; it can increase the risk of stomach bleeding.
  • Avoid exposure to the sunlight because the medication can cause sunburn. So wear protective clothing and apply sunscreen when move outwards after applying the medication.
  • Do not get expose towards sunlight. Naproxen can cause sunburn. Thus wear protective clothing and use sunscreen while going outside.
  • Long term use of the medication can cause increase risk of opposing cardiovascular events.
  • The medication may cause drowsiness, dizziness and blurred vision